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1

The Designer Methcathinone Analogs, Mephedrone and Methylone, are Substrates for Monoamine Transporters in Brain Tissue

Baumann, Michael H, Ayestas, Mario A, Partilla, John S, Sink, Jacqueline R, Shulgin, Alexander T, Daley, Paul F, Brandt, Simon D, Rothman, Richard B, Ruoho, Arnold E, Cozzi, Nicholas V

Journal:

Neuropsychopharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 744 KB

english, 2011

2

Analytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)- threo and (±)- erythro diastereomers

McLaughlin, Gavin, Morris, Noreen, Kavanagh, Pierce V., Power, John D., Dowling, Geraldine, Twamley, Brendan, O'Brien, John, Hessman, Gary, Murphy, Brian, Walther, Donna, Partilla, John S., Baumann, M

Journal:

Drug Testing and Analysis

Année:

2017

Langue:

english

Fichier:

PDF, 655 KB

english, 2017

3

Structural modification of the designer stimulant α-pyrrolidinovalerophenone (α-PVP) influences potency at dopamine transporters

kolanos, renata, Sakloth, Farhana, Jain, Atul D, Partilla, John S, Baumann, Michael H, Glennon, Richard A.

Journal:

ACS Chemical Neuroscience

Année:

2015

Langue:

english

Fichier:

PDF, 555 KB

english, 2015

4

Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone

McLaughlin, Gavin, Morris, Noreen, Kavanagh, Pierce V., Power, John D., Dowling, Geraldine, Twamley, Brendan, O'Brien, John, Talbot, Brian, Walther, Donna, Partilla, John S., Baumann, Michael H., Bran

Journal:

Drug Testing and Analysis

Année:

2016

Langue:

english

Fichier:

PDF, 768 KB

english, 2016

5

Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products

Baumann, Michael H, Partilla, John S, Lehner, Kurt R, Thorndike, Eric B, Hoffman, Alexander F, Holy, Marion, Rothman, Richard B, Goldberg, Steven R, Lupica, Carl R, Sitte, Harald H, Brandt, Simon D, T

Journal:

Neuropsychopharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 573 KB

english, 2013

6

Pharmacology of novel synthetic stimulants structurally related to the “bath salts” constituent 3,4-methylenedioxypyrovalerone (MDPV)

Marusich, Julie A., Antonazzo, Kateland R., Wiley, Jenny L., Blough, Bruce E., Partilla, John S., Baumann, Michael H.

Journal:

Neuropharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2014

7

Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin

Richard B. Rothman, Michael H. Baumann, Christina M. Dersch, Dana V. Romero, Kenner C. Rice, F. Ivy Carroll, John S. Partilla

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 149 KB

english, 2001

8

Binding of the Amphetamine-like 1-Phenyl-piperazine to Monoamine Transporters

Severinsen, Kasper, Kraft, Johan F., Koldsø, Heidi, Vinberg, Katrine A., Rothman, Richard B., Partilla, John S., Wiborg, Ove, Blough, Bruce, Schiøtt, Birgit, Sinning, Steffen

Journal:

ACS Chemical Neuroscience

Année:

2012

Langue:

english

Fichier:

PDF, 4.60 MB

english, 2012

9

Psychoactive “bath salts”: Not so soothing

Baumann, Michael H., Partilla, John S., Lehner, Kurt R.

Journal:

European Journal of Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 366 KB

english, 2013

10

Interaction of psychoactive tryptamines with biogenic amine transporters and serotonin receptor subtypes

Blough, Bruce E., Landavazo, Antonio, Decker, Ann M., Partilla, John S., Baumann, Michael H., Rothman, Richard B.

Journal:

Psychopharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 290 KB

english, 2014

11

Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter

Reith, Maarten E.A., Blough, Bruce E., Hong, Weimin C., Jones, Kymry T., Schmitt, Kyle C., Baumann, Michael H., Partilla, John S., Rothman, Richard B., Katz, Jonathan L.

Journal:

Drug and Alcohol Dependence

Année:

2015

Langue:

english

Fichier:

PDF, 4.89 MB

english, 2015

12

EFFECT OF ACUTE EXERCISE AND ENDURANCE TRAINING ON BETA-ADRENERGIC RECEPTORS IN RAT SKELETAL MUSCLE

Buckenmeyer, P. J., Dax, E. M., Partilla, J. S., Goldfarb, A. H.

Journal:

Medicine & Science in Sports & Exercise

Année:

1986

Fichier:

PDF, 120 KB

1986

13

The dopamine, serotonin and norepinephrine releasing activities of a series of methcathinone analogs in male rat brain synaptosomes

Blough, Bruce E., Decker, Ann M., Landavazo, Antonio, Namjoshi, Ojas A., Partilla, John S., Baumann, Michael H., Rothman, Richard B.

Journal:

Psychopharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 755 KB

english, 2018

14

Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat μ opioid receptor

Yi-Feng Lu, Heng Xu, Lee-Yuan Liu-Chen, Chongguang Chen, John S. Partilla, George A. Brine, F. Ivy Carroll, Kenner C. Rice, Josephine Lai, Frank Porreca, Wolfgang Sadee, Richard B. Rothman

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 171 KB

english, 1998

15

Studies of the biogenic amine transporters. VII. Characterization of a novel cocaine binding site identified with [125I]RTI-55 in membranes prepared from human, monkey and guinea pig caudate

Richard B. Rothman, Mayme L. Silverthorn, John R. Glowa, Dorota Matecka, Kenner C. Rice, F. Ivy Carroll, John S. Partilla, George R. Uhl, David J. Vandenbergh, Christina M. Dersch

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 299 KB

english, 1998

16

Opioid peptide receptor studies, 11: Involvement of Tyr148, Trp318 and His319 of the rat μ-opioid receptor in binding of μ-selective ligands

Heng Xu, Yi-Feng Lu, John S. Partilla, Qiao-Xi Zheng, Jia-Bei Wang, George A. Brine, F. Ivy. Carroll, Kenner C. Rice, Kai-Xian Chen, Zhi-Qiang Chi, Richard B. Rothman

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 135 KB

english, 1999

17

Opioid peptide receptor studies. 12. Buprenorphine is a potent and selective μ/κ antagonist in the [35S]-GTP-γ-S functional binding assay

Dana V. Romero, John S. Partilla, Qaio-Xi Zheng, Simone O. Heyliger, Qing Ni, Kenner C. Rice, Josephine Lai, Richard B. Rothman

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 511 KB

english, 1999

18

Neurochemical neutralization of methamphetamine with high-affinity nonselective inhibitors of biogenic amine transporters: a pharmacological strategy for treating stimulant abuse

Richard B. Rothman, John S. Partilla, Michael H. Baumann, Christina M. Dersch, F. Ivy Carroll, Kenner C. Rice

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 125 KB

english, 2000

19

Probes for narcotic receptor mediated phenomena 22. (1) synthesis and characterization of optically pure [3H](+)-4-[(αR)-α-((2S, 5R)-4-propyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N, N-diethylbenzamide, [3H]SNC 121, a novel high affinity and selective ligand for delta opioid receptors

Silvia N. Calderon, Craig M. Bertha, J. Silvio Gutkind, Heng Xu, John S. Partilla, Richard B. Rothman, Kenner C. Rice

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

1996

Langue:

english

Fichier:

PDF, 236 KB

english, 1996

20

ChemInform Abstract: Development of Novel, Potent, and Selective Dopamine Reuptake Inhibitors Through Alteration of the Piperazine Ring of 1-(2-( Diphenylmethoxy)ethyl)- and 1-(2-(Bis(4-fluorophenyl)methoxy)ethyl)-4-( 3-phenylpropyl)piperazines (GBR 12935 and GBR 12909).

D. MATECKA, R. B. ROTHMAN, L. RADESCA, B. R. DE COSTA, C. M. DERSCH, J. S. PARTILLA, A. PERT, J. R. GLOWA, F. H. E. WOJNICKI, K. C. RICE

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 39 KB

english, 1997

21

Synthesis of [3H]-labelled 4-[Ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3-[3H]-butan-1-ol: a high affinity radioligand for the corticotropin-releasing hormone type 1 receptor

Anne-Cécile Hiebel, John S. Partilla, Richard B. Rothman, Arthur E. Jacobson, Kenner C. Rice

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2006

Langue:

english

Fichier:

PDF, 117 KB

english, 2006

22

High-performance liquid chromatographic resolution of synthetic opiate and “anti-opiate” peptides from human plasma

John S. Partilla, Jingtao You, Richard B. Rothman

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1995

Langue:

english

Fichier:

PDF, 471 KB

english, 1995

23

Uptake and release effects of diethylpropion and its metabolites with biogenic amine transporters

Han Yu, Richard B Rothman, Christina M Dersch, John S Partilla, Kenner C Rice

Journal:

Bioorganic & Medicinal Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 155 KB

english, 2000

24

A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) μ-opioid agonists on cellular markers related to opioid tolerance and dependence

Heng Xu, John S. Partilla, Xiaoying Wang, John M. Rutherford, Kevin Tidgewell, Thomas E. Prisinzano, Laura M. Bohn, Richard B. Rothman

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 370 KB

english, 2007

25

Evidence for noncompetitive modulation of substrate-induced serotonin release

Richard B. Rothman, Michael H. Baumann, Bruce E. Blough, Arthur E. Jacobson, Kenner C. Rice, John S. Partilla

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 498 KB

english, 2010

26

Biosynthesis of dopamine and serotonin in the rat brain after repeated cocaine injections: A microdissection mapping study

Dr. Michael H. Baumann, Thomas J. Raley, John S. Partilla, Richard B. Rothman

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1993

27

Stereochemical requirements for pseudoirreversible inhibition of opioid mu receptor binding by the 3-methylfentanyl congeners, RTI-46144 and its enantiomers: Evidence for different binding domains

Qi Ni, Heng Xu, J. S. Partilla, P. A. Stark, F. I. Carroll, G. A. Brine, R. B. Rothman

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.04 MB

english, 1993

28

6β-[125Iodo]-3, 14-dihydroxy-17-methyl-4, 5α-epoxymorphinan ([125I]IOXY-AGO): A potent and selective radioligand for opioid μ receptors

Heng Xu, Carl B. Goodman, John S. Partilla, Qi Ni, Hiroshi Kayakiri, Kenner C. Rice, Richard B. Rothman

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 1.52 MB

english, 1995

29

Ligand selectivity of cloned human and rat opioid mu receptors

Richard B. Rothman, Heng Xu, Jia Bei Wang, John S. Partilla, Hiroshi Kayakiri, Kenner C. Rice, George R. Uhl

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 513 KB

english, 1995

30

Die Transposition der Venenmündungen

A. Kiss, H. Partilla, E. Pernkopf

Journal:

Virchows Archiv

Année:

1954

Langue:

german

Fichier:

PDF, 5.36 MB

german, 1954

31

Dihydrocodeinone-hydrazone, dihydrocodeinone-oxime, naloxone-3-ome-oxime, and clocinnamox fail to irreversibly inhibit opioid kappa receptor binding

Qing Ni, Heng Xu, John S. Partilla, Brian R. Costa, Kenner C. Rice, Anna Borsodi, Sándor Hosztafi, Richard B. Rothman

Journal:

Neurochemical Research

Année:

1994

Langue:

english

Fichier:

PDF, 491 KB

english, 1994

32

Studies of the biogenic amine transporters. 1. Dopamine reuptake blockers inhibit [3H]mazindol binding to the dopamine transporter by a competitive mechanism: Preliminary evidence for different binding domains

Christina M. Dersch, Hyacinth C. Akunne, John S. Partilla, George U. Char, Brian R. Costa, Kenner C. Rice, F. Ivy Carroll, Richard B. Rothman

Journal:

Neurochemical Research

Année:

1994

Langue:

english

Fichier:

PDF, 795 KB

english, 1994

33

Long-term administration of m-chlorophenylpiperazine (mCPP) to rats induces changes in serotonin receptor binding, dopamine levels and locomotor activity without altering prolactin and corticosterone secretion

Jakob Ulrichsen, John S. Partilla, Elizabeth M. Dax

Journal:

Psychopharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1992

34

Invasion and destruction of a murine fibrosarcoma bySalmonella-induced effector CD8 T cells as a therapeutic intervention against cancer

Elisabeth Roider, Stefan Jellbauer, Brigitte Köhn, Christina Berchtold, Miriam Partilla, Dirk H. Busch, Holger Rüssmann, Klaus Panthel

Journal:

Cancer Immunology, Immunotherapy

Année:

2011

Langue:

english

Fichier:

PDF, 432 KB

english, 2011

35

Methamphetamine Dependence: Medication Development Efforts Based on the Dual Deficit Model of Stimulant Addiction

RICHARD B. ROTHMAN, JOHN S. PARTILLA, CHRISTINA M. DERSCH, F. IVY CARROLL, KENNER C. RICE, MICHAEL H. BAUMANN

Journal:

Annals of the New York Academy of Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2000

36

Serotonin Transporters, Serotonin Release, and the Mechanism of Fenfluramine Neurotoxicity

MICHAEL H. BAUMANN, MARIO A. AYESTAS, CHRISTINA M. DERSCH, JOHN S. PARTILLA, RICHARD B. ROTHMAN

Journal:

Annals of the New York Academy of Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 2.06 MB

english, 2000

37

Effects of “Legal X” Piperazine Analogs on Dopamine and Serotonin Release in Rat Brain

MICHAEL H. BAUMANN, ROBERT D. CLARK, ALLISON G. BUDZYNSKI, JOHN S. PARTILLA, BRUCE E. BLOUGH, RICHARD B. ROTHMAN

Journal:

Annals of the New York Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 4.58 MB

english, 2004

38

N-Substituted Piperazines Abused by Humans Mimic the Molecular Mechanism of 3,4-Methylenedioxymethamphetamine (MDMA, or ‘Ecstasy’)

Baumann, Michael H, Clark, Robert D, Budzynski, Allison G, Partilla, John S, Blough, Bruce E, Rothman, Richard B

Journal:

Neuropsychopharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 179 KB

english, 2004

39

Prognostic significance of the galactose tolerance test in the rhythm of the liver

R. Boller, H. Partilla

Journal:

Digestive Diseases and Sciences

Année:

1958

Langue:

english

Fichier:

PDF, 584 KB

english, 1958

40

Determinants of the stimulation of fat cell adenylate cyclase by high concentrations of sodium and magnesium salts. Implications for the role of magnesium in regulation of enzyme activity

Michael S. Katz, John S. Partilla, Marco A. Pineyro, Robert I. Gregerman

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Année:

1980

Langue:

english

Fichier:

PDF, 531 KB

english, 1980

41

Effects of MDMA and related analogs on plasma 5-HT: Relevance to 5-HT transporters in blood and brain

Samanta Yubero-Lahoz, Mario A. Ayestas Jr., Bruce E. Blough, John S. Partilla, Richard B. Rothman, Rafael de la Torre, Michael H. Baumann

Journal:

European Journal of Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 769 KB

english, 2012

42

TDIQ (5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline) inhibits the consumption of “snacks” in mice

Richard Young, Richard B. Rothman, Jagadeesh B. Rangisetty, John S. Partilla, Malgorzata Dukat, Richard A. Glennon

Journal:

Pharmacology Biochemistry and Behavior

Année:

2006

Langue:

english

Fichier:

PDF, 185 KB

english, 2006

43

Interaction of the anorectic medication, phendimetrazine, and its metabolites with monoamine transporters in rat brain

Richard B Rothman, Marina Katsnelson, Nga Vu, John S Partilla, Christina M Dersch, Bruce E Blough, Michael H Baumann

Journal:

European Journal of Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 231 KB

english, 2002

44

Zur Diagnostik des Hinterwandinfarktes und des Hinterwandancurysmas im Elektrokardiogramm.

L. SLAPAK, H. PARTILLA

Journal:

Journal of Internal Medicine

Année:

1950

Langue:

german

Fichier:

PDF, 813 KB

german, 1950

45

Iodate promotes guanosine triphosphate stimulation of human fat-cell adenylate cyclase

Thomas M. Kelly, Michael S. Katz, Marco A. Piñeyro, John S. Partilla, Robert I. Gregerman

Journal:

Archives of Biochemistry and Biophysics

Année:

1982

Langue:

english

Fichier:

PDF, 823 KB

english, 1982

46

Human fat cell adenylate cyclase: Enzyme characterization and guanine nucleotide effects on epinephrine responsiveness in cell membranes

Barry Cooper, John S. Partilla, Robert I. Gregerman

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Année:

1976

Langue:

english

Fichier:

PDF, 774 KB

english, 1976

47

Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors

Heng Xu, Xiaoying Wang, John S. Partilla, Kristen Bishop-Mathis, Tova S. Benaderet, Christina M. Dersch, Denise S. Simpson, Thomas E. Prisinzano, Richard B. Rothman

Journal:

Brain Research Bulletin

Année:

2008

Langue:

english

Fichier:

PDF, 498 KB

english, 2008

48

Evidence for a μ–δ opioid receptor complex in CHO cells co-expressing μ and δ opioid peptide receptors

John M. Rutherford, Jiabei Wang, Heng Xu, Christina M. Dersch, John S. Partilla, Kenner C. Rice, Richard B. Rothman

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 477 KB

english, 2008

49

Region-specific up-regulation of opioid receptor binding in enkephalin knockout mice

Linda S Brady, Miles Herkenham, Richard B Rothman, John S Partilla, Monica König, Anne M Zimmer, Andreas Zimmer

Journal:

Molecular Brain Research

Année:

1999

Langue:

english

Fichier:

PDF, 1.74 MB

english, 1999

50

Opioid Peptide Receptor Studies. 8. One of the Mouse Brain δNCX Binding Sites is Similar to the Cloned Mouse Opioid δ Receptor: Further Evidence for Heterogeneity of δ Opioid Receptors

Heng Xu, Yi-Feng Lu, John S Partilla, Julia Pinto, Sylvia N Calderon, Dorota Matecka, Kenner C Rice, Josephine Lai, Frank Porreca, Subramaniam Ananthan, Richard B Rothman

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 85 KB

english, 1998